Is it not similar to what Paul speaks of in 1 Corinthians 6:16?
16 Or do you not know that he who is joined to a prostitute becomes one body with her? For, as it is written, “The two will become one flesh.”
Have we not 'joined' ourselves with sin and become one body with her? My feeble understanding of 'knowing good and evil' like God means we know what sin is and we know what is right. However, unlike God, we choose to 'join' ourselves to sin. I don't say this hopelessly, though.
2 Corinthians 5:21
21 For our sake he made him to be sin who knew no sin, so that in him we might become the righteousness of God.
Jesus Christ knew what sin was. He preached against it for 3 years, but He did not 'know' it. He was led into the wilderness and Satan tried to entice Him to 'join' Himself with sin. But He was/is God.
Hebrews 4:15
15 For we do not have a high priest who is unable to sympathize with our weaknesses, but one who in every respect has been tempted as we are, yet without sin.
Romans 7:1-4
1 Or do you not know, brothers—for I am speaking to those who know the law—that the law is binding on a person only as long as he lives? 2 For a married woman is bound by law to her husband while he lives, but if her husband dies she is released from the law of marriage. 3 Accordingly, she will be called an adulteress if she lives with another man while her husband is alive. But if her husband dies, she is free from that law, and if she marries another man she is not an adulteress.
4 Likewise, my brothers, you also have died to the law through the body of Christ, so that you may belong to another, to him who has been raised from the dead, in order that we may bear fruit for God.
So, like God, we knew good and evil. But unlike God, we chose evil and we joined ourselves to it and were married to it. But by His grace, we died so that our marriage no longer bound us and we could marry Another.